Morphological transformation of rod-shaped bacterial cells: mechanisms and biological impacts
WANG Lei1,*, ZOU Lin1,*, LI Mengjie1, HOU Linlin1, CHEN Xiaoming2, LIU Wei2, SUN Guiqin3, CHEN Li1
1. Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; 2. Key Laboratory of Research on Hydraulic and Hydro-Power Equipment Surface Engineering Technology of Zhejiang Province, Hangzhou 310024, Zhejiang Province, China; 3. College of Medical Technology, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China
Abstract:Cell shape is a basic core feature for bacterial classification and identification. Although a bacterium could be defined as coccus, bacillus, vibrio or spirochete, morphological transformations were observed under various physiological and pathological conditions. In this paper, the molecular mechanisms of rod-shaped bacterial morphological transformation are reviewed, and the biological impacts of morphological transformation under nutritional deficiency, radiation, antibiotic treatment and attacking by host immune systems are discussed.
王蕾1,*,邹琳1,*,李梦洁1,侯琳琳1,陈小明2,刘伟2,孙桂芹3,陈力1. 杆菌细胞形变的机制与功能[J]. 微生物与感染, 2019, 14(2): 99-105.
WANG Lei1,*, ZOU Lin1,*, LI Mengjie1, HOU Linlin1, CHEN Xiaoming2, LIU Wei2, SUN Guiqin3, CHEN Li1. Morphological transformation of rod-shaped bacterial cells: mechanisms and biological impacts. JOURNAL OF MICROBES AND INFECTIONS, 2019, 14(2): 99-105.