杆菌细胞形变的机制与功能

王蕾1; *; 邹琳1; *; 李梦洁1; 侯琳琳1; 陈小明2; 刘伟2; 孙桂芹3; 陈力1

doi:10.3969/j.issn.1673-6184.2019.01.005

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微生物与感染 ›› 2019, Vol. 14 ›› Issue (2) : 99-105. DOI: 10.3969/j.issn.1673-6184.2019.01.005

综述

杆菌细胞形变的机制与功能

王蕾^1，*，邹琳^1，*，李梦洁¹，侯琳琳¹，陈小明²，刘伟²，孙桂芹³，陈力¹

作者信息 +

Morphological transformation of rod-shaped bacterial cells: mechanisms and biological impacts

WANG Lei^1，*, ZOU Lin^1，*, LI Mengjie¹, HOU Linlin¹, CHEN Xiaoming², LIU Wei², SUN Guiqin³, CHEN Li¹

Author information +

文章历史 +

摘要

细菌的形态是细菌分类与鉴定的核心指标。虽然在分类上细菌的基本形态有球形、杆状、弧形和螺旋形，但在不同生理和病理条件下细菌的形态会发生改变。本文对细菌的基本形态转变和杆菌的丝状形变分子机制进行了概述，并归纳了在营养缺乏、放射污染、对抗宿主免疫系统和抗生素处理等条件下细菌产生形态改变的生物学及临床意义。

Abstract

Cell shape is a basic core feature for bacterial classification and identification. Although a bacterium could be defined as coccus, bacillus, vibrio or spirochete, morphological transformations were observed under various physiological and pathological conditions. In this paper, the molecular mechanisms of rod-shaped bacterial morphological transformation are reviewed, and the biological impacts of morphological transformation under nutritional deficiency, radiation, antibiotic treatment and attacking by host immune systems are discussed.

导出引用

王蕾1，*，邹琳1，*，李梦洁1，侯琳琳1，陈小明2，刘伟2，孙桂芹3，陈力1. 杆菌细胞形变的机制与功能[J]. 微生物与感染. 2019, 14(2): 99-105 https://doi.org/10.3969/j.issn.1673-6184.2019.01.005

WANG Lei1，*, ZOU Lin1，*, LI Mengjie1, HOU Linlin1, CHEN Xiaoming2, LIU Wei2, SUN Guiqin3, CHEN Li1. Morphological transformation of rod-shaped bacterial cells: mechanisms and biological impacts[J]. Journal of Microbes and Infections. 2019, 14(2): 99-105 https://doi.org/10.3969/j.issn.1673-6184.2019.01.005