1. Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS)，School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China; 2. Division of Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA; 3. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA; 4. Children’s Hospital of Fudan University, Shanghai 201102, China
Abstract：Noroviruses are the most important viral pathogens causing epidemic acute gastroenteritis infecting people of all ages around the world. The viruses are responsible for the most common non-bacterial foodborne outbreaks of diarrhea. Due to the lack of an effective cell culture or small animal research model, the pathogenesis of norovirus infection and illness remains unclear. By contrast, norovirus laboratory diagnostic technologies are well developed. The recent applications of new technologies are further enhancing the development of diagnostic tools to meet the needs of public health and clinical diagnosis and treatment.
2019, Vol. 14 
