摘要
新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)在中国武汉暴发波及全国,截至2月14日,死亡人数已经超过 1 300,严重威胁人类的生命。《新型冠状病毒感染的肺炎诊疗方案(试行第五版)》中采用的抗病毒、抗细菌、激素、机械通气和循环支持等治疗手段,均为引发真菌感染的高危因素。当患者继发真菌感染时,病死率会大幅提升。因此,应制定科学、规范的预警技术,以便早期发现真菌感染;研发便捷、高效、低廉和覆盖面广的抗高发侵袭性真菌感染的诊断试剂盒以及新型抗菌材料防护物品,确保做到早期预警、明确诊断、精准治疗和有效防护,以应对可能出现的COVID-19继发严重真菌感染的状况。密切关注COVID-19并发、继发性真菌感染具有重要的现实意义。
Abstract
Coronavirus disease 2019 (COVID-19) broke out in Wuhan, China and spread throughout the country. Up to now, the death toll has exceeded one thousand. Most of the treatments listed in the latest edition of diagnosis and treatment scheme, such as antiviral and antibacterial therapy, hormonotherapy, mechanical ventilation, and supportive treatment, are high risk factors for secondary fungal infections. As the mortality rate of patients with secondary fungal infection could be doubled, targeted prevention and treatment for secondary fungal infection is of great significance for COVID-19.
关键词
新型冠状病毒肺炎 /
继发性真菌感染 /
诊断 /
治疗 /
预警
Key words
Coronavirus disease 2019 /
Secondary fungal infection /
Diagnosis /
Treatment /
Warning
潘炜华,廖万清.
密切关注新型冠状病毒肺炎并发、继发侵袭性真菌感染[J]. 微生物与感染. 2020, 15(1): 7-11 https://doi.org/10.3969/j.issn.1673-6184.2020.01.002
Pan Weihua,Liao Wanqing.
Pay close attention on secondary fungal infections of coronavirus disease 2019[J]. Journal of Microbes and Infections. 2020, 15(1): 7-11 https://doi.org/10.3969/j.issn.1673-6184.2020.01.002
中图分类号:
R373
R379
R512.99
R519.8
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基金
“十三五”国家科技重大专项(2018ZX10101003), 上海市卫健委临床重点专科基金(2017ZZ01024-001),上海市科委重点实验室基金(17DZ2272900)