Abstract：The Chinese government has been paying close attention to biosafety practice in pathogen research laboratories since the occurrence of severe acute respiratory syndrom( SARS) outbreaks. There are measures in place for the management of the biosafety level-1 ( BSL-1 ) , BSL-2 pathogenic microbiology laboratories, including experimental details of operation, conditions of study equipment, and personnel training assessments. The management of laboratory biosafety is related to economic development of the region, social stability, and public health. Any negligence to safety events may cause irreparable loss. With advanced computer technology, this study aimed to set up a management system model for BSL-1 and BSL-2 laboratories, in accordance with conditions of domestic pathogenic microbiology laboratories, to meet the growing demand of standardized laboratory biosafety via the integration of presently effective international practice on laboratory biosafety of pathogenic microorganisms. Internal assessments were verified by the Shanghai Public Health Clinical Center Affiliated to Fudan University.
