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Abstract Abstract: Fecal microbiota transplantation (FMT) is an innovative method to reconstruct the balance of intestinal microbiota by transplanting Fecal microbiota from healthy donors to patients with diseases, which provides help for the treatment of diseases. In the treatment of recurrent refractory Clostridium difficile infection, the efficacy is very good. In recent years, its therapeutic potential has not only been limited to gastrointestinal diseases, but also has been continuously explored in other microbial-related diseases. Although the gut bacteriome plays an important role in the pathogenesis of gastrointestinal diseases, in addition to the gut bacteriome, the gut bacteriophage group also plays a great role. The impact of intestinal phages on the success of FMT treatment has only recently been appreciated. This review summarizes the latest literature on intestinal phages and the impact of FMT on various diseases, and discusses and emphasizes the role of phages in the efficacy and safety, in order to improve the understanding of the role of intestinal phages in FMT and provide information for better clinical practice.
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Received: 15 November 2022
Published: 01 January 2023
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