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Research progresses on drug resistance and transmission mechanisms of Pseudomonas aeruginosa to β-lactam antibiotics |
SUN Qing-Ju, LIANG Bing |
Department of Laboratory Medicine, 401 Hospital of PLA, Qingdao 266071, China |
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Abstract Pseudomonas aeruginosa is a conditional pathogen and the leading species isolated from hospitalacquired infections. With the increasing and unrational usage of antibiotics , the resistance of Pseudomonas aeruginosa to β-lactam antibiotics has gradually increased, and then the anti-infection therapy in hospitals becomes even more difficult. The resistance mechanism of Pseudomonas aeruginosa to β-lactam antibiotics is complex, including natural and acquired drug-resistance. In this paper, the recent researches on mechanisms of resistance to β-lactam antibiotics and transmission of Pseudomonas aeruginosa are reviewed.
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Received: 20 August 2012
Published: 25 June 2013
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Corresponding Authors:
LIANG Bing
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