本文对1例纹带棒状杆菌(Corynebacterium striatum)引发老年患者肺部感染的病例进行报道。患者男性，93岁，入院前2个月诊断为“吸入性肺炎”，给予哌拉西林他唑巴坦钠、亚胺培南西司他丁钠及左氧氟沙星进行治疗，但患者肺部感染难以控制，改用美洛培南进行抗感染治疗，效果欠佳。后经验性加用氟康唑抗真菌治疗，肺部感染仍迁延不愈，症状加重。痰培养报告提示，纹带棒状杆菌(＋＋＋＋)，利奈唑胺对其的抑菌圈直径大。考虑上述治疗方案欠佳，停用氟康唑，调整为美洛培南联合利奈唑胺抗感染。此次调整抗菌药物10天后，患者咳嗽、咳痰症状逐步好转。后将美洛培南降阶为左氧氟沙星联合利奈唑胺抗感染，降阶治疗2天后，患者肺部感染好转，遂停用抗菌药物，肺部感染治疗成功。

This paper reports a case of pulmonary infection caused by Corynebacterium striatum in an elderly patient. The patient, male, 93 years old, was treated with piperacillin-tazobactam, imipenem-cilastatin and levofloxacin due to “aspiration pneumonia” two months ago. The patient’s pulmonary infection was difficult to control, and meropenem was upgraded for anti-infection, but the effect was not good. After empiric antifungal treatment with fluconazole, the pulmonary infection continued to persist and the symptoms worsened. Sputum culture result suggested Corynebacterium striatum (＋＋＋＋), and linezolid showed a large diameter inhibitory zone against the bacteria. Considering the previous treatment plan was not satisfactory, fluconazole was discontinued and the regimen was adjusted to meropenem combined with linezolid for anti-infection. Ten days after the adjustment of the antimicrobial agents, the patient’s symptoms of cough and sputum production gradually improved. Subsequently, meropenem was de-escalated to levofloxacin combined with linezolid for anti-infection. After 2 days of de-escalation therapy, the patient’s pulmonary infection improved, and the antimicrobial agents were discontinued, resulting in successful treatment of the pulmonary infection.