摘要
目的 分析人类免疫缺陷病毒(HIV)感染者的临床特点及其意义。方法 用微粒酶免疫试验和蛋白质印迹法对HIV感染者的血清进行HIV抗体初筛和确认,并对感染者的流行病学、机会性感染及免疫学特点进行分析。结果 在1998~2006年期间,我院共发现77例HIV感染者,其中上海户籍患者占了50.7%,男、女比例为2.85∶1,年龄以30~49岁为主,传播途径中以性传播最常见(40.3%)。早期症状常被忽略,以消化道及肺部真菌、假单胞菌感染,性传播疾病,病毒性肝炎,皮损等就诊于各科室。多重或多部位的机会性感染可见于大多数临床已发病患者。结论 HIV感染的及时诊断,对感染者的治疗、机会性感染的预防以及减少传播具有重要的意义。
Abstract
Objective To analyze clinical characteristics of HIV infection.Methods HIV antibody was screened by third generation of Abbott reagent(MEIA,S/O≥1.00),and confirmed by the Center of Diseases Prevention and Control of Shanghai using Western Blot assay. The characteristics of epidemiology,opportunistic infections,immunology in these patients were analyzed. Results 77 HIV infected individuals were confirmed to HIV positive during 1998-2006 in Rui Jin Hospital. Among these 50.7% were Shanghai residence. The ratio of male to female was 2.85∶1, mostly among people of 30-49 years old and predominantly infected by sex(40.3%). The early manifestations of illness were often neglected. Fungal infection of digestive and pulmonary system,Pseudomonas aeruginosa infection,STD,viral hepatitis,dermatopathy were observed in many departments. The characteristic of patients with symptoms was infections at multiple sites or infected with multiple microbes.Conclusion Timely clinical diagnosis of HIV infection is important for treatment of patients which can prevent opportunistic infections and transmission of the virus.
关键词
抗体 /
临床特征
Key words
Human immunodeficiency virus /
Antibody /
Clinical characteristics
龚启明; 仇德琪; 陆志檬; 张欣欣.
77例人类免疫缺陷病毒感染者临床特征分析[J]. 微生物与感染. 2007, 2(2): 92-94
GONG Qi-ming; QIU De-qi; Lu Zhi-meng; ZHANG Xin-xin.
The analysis of clinical characteristics in 77 HIV infected individuals[J]. Journal of Microbes and Infections. 2007, 2(2): 92-94
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