产单核细胞李斯特菌常引起新生儿、孕产妇、老年人和免疫受抑者患菌血症和脑膜炎。其血流感染发病率低, 但病死率很高, 病原学诊断复杂。本文报道1 例以聚合酶链反应方法确诊的产单核细胞李斯特菌血流感染, 以提高临床微生物学工作者对该病原菌生物学特性和实验室检测方法的认识。

Listeria monocytogenes ( LM) is an important pathogen causing bacteremia and meningoencephalitis among newborns, pregnant women, the elderly, and immunosuppressed patients. Low incidence but high mortality characterizes a bloodstreaminfection caused by LM. Isolation and identification of LMare not easy in the clinical microbiology laboratory. In the present paper, acase of LM blood infection is presented, whichwas diagnosed rapidly by amplifying prfA gene through polymerase chain reaction in addition to traditional microbiological assays.