本文旨在回顾性分析2003年1月～2008年12月上海交通大学附属第六人民医院收治的220例成人麻疹患者临床资料,探讨成人麻疹患者临床特征。220例患者(男124例,女96例),平均年龄(34.6±4.2)岁,外来人员占70.91%,发病集中于4、5月,血清麻疹IgM抗体阳性率为93.18%,183例(83.18%)热峰高于39℃,86例(39.09%)并发麻疹病毒性肝炎,31例(14.09%)并发腹泻。麻疹发病年龄后移,具有较重的病毒血症以及肝脏损害等临床特征。

The present paper aims to retrospectively analyze the clinical data of 220 patients with adult measles in Shanghai Sixth People’s Hospital , Shanghai Jiao Tong University ,from January 2003 to December 2008，and to evaluate the clinical characteristics of adult measles. The patients included 124 males and 96 females.The average age was(34.6±4.2)years old and the proportion of migrating population who are not regular Shanghai residents was 70.91%. The incidence peak of adult measles appeared in April and May, and the positive rate of measles virus-specific serum IgM was 93.18%. There were 183 patients (83.18%)with fever above 39℃, 86 patients (39.09%) and 31 patients (14.09%)concurrent with viral hepatitis and diarrhea, respectively. Our study highlighted the importance of postponed onset of measles in adults including people with history of vaccination as shown by serious toxemic symptoms and liver injuries.