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PDF(462 KB)
PDF(462 KB)
双唑泰泡腾片与乳酸杆菌活菌胶囊联合治疗细菌性阴道病的临床疗效分析
Clinical effects of combination of metronidazole, clotrimazole and chlorhexidine acetate effervescent tablets and living preparationof lactobacillus on bacterial vaginosis
本文旨在探讨双唑泰泡腾片与乳杆菌活菌胶囊联合治疗细菌性阴道病的临床疗效。将100例就诊于江苏省中西医结合医院妇产科的细菌性阴道病患者随机平均分为两组:治疗组给予阴道内放置双唑泰泡腾片与乳杆菌活菌胶囊联合治疗;对照组单用阴道内放置双唑泰泡腾片。结果显示,治疗组细菌性阴道病48例(失访2例),35例显效,8例有效,显效率为 72.92%,总有效率为 89.58%;对照组细菌性阴道病49例(失访1例),31例显效,7例有效,显效率为 63.27%,总有效率为 77.56%。两组总有效率有显著性差异(P<0.05)。治愈者在停药后第4周复查,治疗组复发3例,复发率为6.25%;对照组复发10例,复发率为 20.41%。两组比较有显著性差异(P<0.05)。结果提示,双唑泰泡腾片与乳杆菌活菌胶囊联合治疗细菌性阴道病安全有效,值得临床推广。
The present paper aims to investigate the clinical effects of combination of metronidazole, clotrimazole and chlorhexidine acetate effervescent tablets and living preparationof lactobacillus on bacterial vaginosis. A total of 100 patients with bacterial vaginosis from the Department of Obstetrics and Gynecology, Hospital of Chinese and Western Integrated Medicine of Jiangsu Province were selected and equally divided into the control group and experimental group. The patients in the control group were only treated with metronidazole, clotrimazole and chlorhexidine acetate effervescent tablets, and the patients in the experimental group were treated with combination of metronidazole, clotrimazole and chlorhexidine acetate effervescent tablets and living preparationof lactobacillus. The curative effects in the two groups were compared after treatment. In the experimental group, 2 cases were lost to follow-up, 35 markedly effective, 8 effective. The markedly effective rate was 72.92% and the total effective rate was 89.58%. In the control group, 1 case was lost to follow-up, 31 markedly effective, 7 effective. The markedly effective rate was 63.27% and the total effective rate was 77.56%. The total effective rate was significantly different in two groups (P<0.05). The recurrence rate in the experimental group was 6.25%, significantly lower than 20.41% in the control group (P<0.05). The results suggest that combination of metronidazole, clotrimazole and chlorhexidine acetate effervescent tablets and living preparation of lactobacillus is safe and effective in treatment of bacterial vaginosis.
Bacterial vaginosis / Metronidazole, clotrimazole, and chlorhexidine acetate effervescent tablets / Lliving preparation of lactobacillus
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