含ICE-emm12和ΦHKU.vir化脓链球菌引起的猩红热1例

沈银芳1,陈明亮2, 3,陈敏2,王建设1,张曦2

微生物与感染 ›› 2016, Vol. 11 ›› Issue (5) : 293-296.

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微生物与感染 ›› 2016, Vol. 11 ›› Issue (5) : 293-296.
病例分析

含ICE-emm12和ΦHKU.vir化脓链球菌引起的猩红热1例

  • 沈银芳1,陈明亮2, 3,陈敏2,王建设1,张曦2
作者信息 +

One case of scarlet fever caused by Streptococcus pyogenes with ICE-emm12 and ΦHKU.vir

  • SHEN Yinfang1,CHEN Mingliang2,3,CHEN Min2,WANG Jianshe1,ZHANG Xi2
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文章历史 +

摘要

2011年中国开始出现猩红热疫情,病例以普通型为主,外科型较少报道。ICE-emm12和ΦHKU.vir是中国香港地区猩红热暴发株中首次发现的2个可移动遗传元件,尚不清楚其是否存在于中国内地的猩红热致病株中。本文报道1例猩红热病例,其咽部和皮肤伤口皆分离出同一克隆株的化脓链球菌,该菌株携带ICE-emm12和ΦHKU.vir,从而证实这2个新元件存在于中国内地的化脓链球菌中。因此,国内有必要对猩红热分离株进行ICE-emm12和ΦHKU.vir检测,以监测致病株在基因水平的变化。

Abstract

Epidemics of scarlet fever started in China in 2011. Most of the cases were represented by the classic type, while the surgical type was rarely reported. It is unclear whether ICE-emm12 and ΦHKU.vir, the two mobile genetic elements firstly discovered in the strains leading to scarlet fever outbreak in Hong Kong, were carried by the strains in Mainland China. Here we reported a scarlet fever case in Zhejiang which was caused by Streptococcus pyogenes. Strains isolated from the pharynx and skin wound all carried ICE-emm12 and ΦHKU.vir. The result suggests a screening of the two mobile genetic elements in Mainland China for genetic surveillance of scarlet fever.

关键词

猩红热 / 化脓链球菌 / 可移动遗传元件

Key words

Scarlet fever / Streptococcus pyogenes / Mobile genetic element

引用本文

导出引用
沈银芳1,陈明亮2, 3,陈敏2,王建设1,张曦2. 含ICE-emm12和ΦHKU.vir化脓链球菌引起的猩红热1例[J]. 微生物与感染. 2016, 11(5): 293-296
SHEN Yinfang1,CHEN Mingliang2,3,CHEN Min2,WANG Jianshe1,ZHANG Xi2. One case of scarlet fever caused by Streptococcus pyogenes with ICE-emm12 and ΦHKU.vir[J]. Journal of Microbes and Infections. 2016, 11(5): 293-296

基金

上海市自然科学基金(16ZR1433300),上海市卫生和计划生育委员会第四轮公共卫生三年行动计划项目(GWTD2015S01、15GWZK0101)


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