曲霉菌为条件致病菌,可引起侵袭性曲霉菌病、慢性肺曲霉菌病、变态反应性支气管肺曲霉菌病,亦可引起皮肤、骨骼等部位感染及曲霉毒素中毒。曲霉引起的腹膜炎相对少见,但其严重程度和病死率相对较高,它与腹膜透析患者的高死亡率和发病率相关。目前国内尚未见由黄曲霉引起腹膜炎的报道。文章报道1例腹透患者细菌性腹膜炎继发黄曲霉感染的病例,最终通过菌种的精准鉴定以及准确的药敏结果,从而达到有效治疗的过程。旨在加深对黄曲霉的认识,为临床早期诊断、及时检测和有效治疗提供重要的指导意义。
Abstract
Aspergillus is an opportunistic pathogen, which can cause invasive aspergillosis, chronic pulmonary aspergillosis, allergic bronchopulmonary aspergillosis, and can also cause skin, bone and other parts of the infection and aspergillus poisoning. Peritonitis caused by Aspergillus is relatively rare, but its severity and mortality are relatively high, and it is associated with high mortality and morbidity in peritoneal dialysis patients. Peritonitis caused by Aspergillus flavus has not been reported in China. We report a case of Aspergillus flavus infection secondary to a bacterial peritonitis in a patient with peritoneal penetration, and finally received effective treatment through accurate identification of isolates and accurate antimicrobial susceptibility results. The aim of this study is to deepen the understanding of Aspergillus flavus and provide important guidance for early diagnosis, timely detection, and effective treatment in clinical practice.
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