摘要：目的 分析肿瘤患者导管相关血流感染(CLABSI)支气管戈登菌的分离鉴定及药敏特点，为临床治疗该菌引起的感染性疾病提供参考。方法 采集1例子宫内膜癌患者放疗后分别经静脉导管和外周静脉留取的血培养阳性标本，同时采用VITEK MS全自动微生物质谱检测系统和分子测序技术对该分离株进行鉴定分析,并参照诺卡菌和其他需氧放线菌药敏试验标准进行药敏试验。结果 静脉导管血需氧瓶和外周静脉血需氧瓶孵育48h后阳性报警，涂片见革兰阳性杆菌。血琼脂平板上培养24h，生长不溶血白色粗糙干燥菌落，培养至48h，白色粗糙干燥菌落转变为橘黄色粗糙干燥菌落。VITEK MS质谱仪和16S rRNA测序技术均鉴定为支气管戈登菌（Gordonia bronchialis），药敏结果表明该菌对万古霉素、头孢曲松、头孢吡肟、环丙沙星、亚胺培南、美罗培南、利奈唑胺、复方新诺明敏感。 结论 本研究报告了支气管戈登菌的生物学特征和病例的诊疗过程，尽管该菌在环境中很常见，但与人类疾病相关的案例相对较少。与所有微生物感染一样，对于疑似或确诊的支气管戈登菌感染，应该进行及时的诊断和治疗。

Abstract： Objective To analyze the isolation, identification and drug sensitivity of Gordonia bronchialis in tumor patients with catheter related bloodstream infection, and provide reference for clinical treatment of infectious diseases caused by this bacteria. Method The blood culture positive sample was collected from a patient with endometrial cancer after radiotherapy, which was collected through venous catheter and peripheral vein. At the same time, the isolate was identified and analyzed by using VITEK MS fully automated microbial mass spectrometry detection system and molecular sequencing technology, and the drug sensitivity tests were conducted according to the Gram positive rod bacteria drug sensitivity test standards. Result After incubating the venous catheter blood and peripheral venous blood for 48 hours, a positive alarm was reported, and Gram positive bacteria were found on the smear. Cultivated on a blood agar plate for 24 hours, it grew non hemolytic bacterial colonies which were white,rough and dry. After 48 hours of cultivation, the white ,roug hand dry bacterial colonies transformed into orange, rough and dry bacterial colonies. The VITEK MS mass spectrometer and 16S rRNA sequencing technology both identified that this bacterium was Gordon bronchialis, and the drug sensitivity results showed that this bacterium was sensitive to vancomycin, ceftriaxone, cefepime, ciprofloxacin, imipenem, meropenem, linezolid, and compound sulfamethoxazole. Conclusion This study reports the biological characteristics and diagnosis and treatment process of Gordonia bronchialis. Although this bacterium is common in the environment, there are relatively few cases related to human diseases. Like all microbial infections, timely diagnosis and treatment should be carried out for suspected or confirmed Gordonia bronchialis's infection.