Epstein-Barr病毒相关淋巴瘤的研究进展
Research advances in Epstein-Barr virus-associated lymphoma
Received date: 2017-09-01
Online published: 2018-02-25
Epstein-Barr病毒(Epstein-Barr virus,EBV)是第1个被发现与人类肿瘤发生相关的病毒,且越来越多的数据表明其感染与某些淋巴瘤的发生发展、治疗及预后密切相关。近年来免疫治疗手段发展迅速,但EBV阳性淋巴瘤的治疗目前主要仍以放化疗为基础,结合抗病毒药物。因此,加强EBV及其相关淋巴瘤的研究,寻找有效预防或治疗EBV感染的方法,将有望改善EBV阳性淋巴瘤患者的预后。
关键词: Epstein-Barr病毒; 淋巴瘤; 治疗; 预后
谷晓宇 , 谢彦晖 . Epstein-Barr病毒相关淋巴瘤的研究进展[J]. 微生物与感染, 2018 , 13(1) : 2 -7 . DOI: 10.3969/j.issn.1673-6184.2018.01.002
Epstein-Barr virus (EBV) is the first virus found in humans to be associated with tumorigenesis. More and more studies have found that EBV infection is closely related with the occurrence, development, treatment and prognosis of some lymphomas. To date, although the application of antiviral drugs and immunotherapy is rapidly developed, the treatment against EBV-positive lymphomas is still mainly based on radiotherapy and chemotherapy. To strengthen the research on EBV and EBV-related lymphomas, and seeking effective prevention or treatment strategies against EBV infection, will be expected to improve the prognosis of patients with EBV-positive lymphomas.
Key words: Epstein-Barr virus; Lymphoma; treatment; prognosis
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