多重耐药和广泛耐药鲍曼不动杆菌感染治疗的药物选择

张驰1; 2; 凌保东1; 2

doi:10.3969/j.issn.1673-6184.2018.02.005

微生物与感染 >

2018 , Vol. 13 >Issue 2: 90 - 96

DOI: https://doi.org/10.3969/j.issn.1673-6184.2018.02.005

综述

多重耐药和广泛耐药鲍曼不动杆菌感染治疗的药物选择

张驰1 ,
2 ,
凌保东1 ,
2

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1. 成都医学院结构特异性小分子药物研究四川省高校重点实验室，成都 610500; 2. 成都医学院非编码RNA与药物实验室，成都 610500

收稿日期: 2017-06-21

网络出版日期: 2017-04-25

基金资助

国家自然科学基金(81373454)，四川省科技厅应用基础项目(2013Jy0065)

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Treatment options for multidrug-resistant and extensively drug-resistant Acinetobacter baumannii infections

ZHANG Chi1 ,
2 ,
LING Baodong1 ,
2

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1. Small Molecule Drugs Key Laboratory of Sichuan Province, Institute of Materia Medica, Chengdu Medical College, Chengdu 610500, China; 2. Non-coding RNA and Drug Discovery Laboratory, Chengdu Medical College, Chengdu 610500, China

Received date: 2017-06-21

Online published: 2017-04-25

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摘要

鲍曼不动杆菌是医院内感染的重要病原体，其基于内在性和获得性的耐药机制，导致全球抗感染领域面临巨大挑战。目前，针对多重耐药和广泛耐药鲍曼不动杆菌引起的感染尚无有效治疗方案，本文对其可选用的治疗药物及最新进展进行综述。

关键词： 多重耐药鲍曼不动杆菌; 广泛耐药鲍曼不动杆菌; 抗感染治疗

本文引用格式

张驰1 , 2 , 凌保东1 , 2 . 多重耐药和广泛耐药鲍曼不动杆菌感染治疗的药物选择[J]. 微生物与感染, 2018 , 13(2) : 90 -96 . DOI: 10.3969/j.issn.1673-6184.2018.02.005

Abstract

Acinetobacter baumannii (A. baumannii) is the major pathogen causing nosocomial infectious diseases in the world due to various intrinsic and acquired mechanisms of drug resistance. There are no effective treatments for the infections caused by multidrug-resistant A. baumannii and extensively-resistant A. baumannii. This review lists standard drugs and new options for the treatment.

Key words： Multidrug-resistant Acinetobacter baumannii; Extensively-resistant Acinetobacter baumannii; Anti-infection therapy

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