冠状病毒疫苗的研究进展

崔文禹; 徐静

doi:10.3969/j.issn.1673-6184.2020.04.001

微生物与感染 >

2020 , Vol. 15 >Issue 4: 199 - 205

DOI: https://doi.org/10.3969/j.issn.1673-6184.2020.04.001

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冠状病毒疫苗的研究进展

崔文禹 ,
徐静

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国药中生生物技术研究院有限公司，北京 101111

收稿日期: 2020-03-01

网络出版日期: 2020-08-25

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Recent advances in the vaccine development against coronavirus

CUI Wenyu ,
XU Jing

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National Vaccine & Serum Institute ,Beijing 101111,China

Received date: 2020-03-01

Online published: 2020-08-25

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摘要

严重急性呼吸综合征冠状病毒2(severe acute respiratory syndrome coronavirus 2，SARS-CoV-2)自被发现以来就引起了人们的广泛关注，开发针对该病毒的安全、有效疫苗成为近期的研究热点。本文以高致病性冠状病毒疫苗(包括灭活疫苗、重组亚单位疫苗、重组病毒载体疫苗和核酸疫苗)的研究展开综述，为研制SARS-CoV-2疫苗提供参考。

关键词： 严重急性呼吸综合征冠状病毒2; 冠状病毒; 疫苗

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崔文禹 , 徐静 . 冠状病毒疫苗的研究进展[J]. 微生物与感染, 2020 , 15(4) : 199 -205 . DOI: 10.3969/j.issn.1673-6184.2020.04.001

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has attracted attention worldwide. The development of safe and effective vaccines against this virus has become an urgent need. This article reviews the research on coronavirus vaccines, including inactivated vaccines, genetically engineered recombinant subunit vaccines, nucleic acid vaccines, and viral vector-based vaccines.

Key words： Severe acute respiratory syndrome coronavirus 2; Coronavirus; Vaccine

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