Evaluation and research progress of varicella-zoster virus vaccines
YI Xing-Xu 1, GAN Lin1, CHEN Jing-Xian1,2, WANG Ming-Li1
1. Department of Microbiology, Anhui Medical University, Hefei 230032, China；2. Department of Pathology and Cell Biology, Columbia University, New York 10032, USA
Abstract：Varicellazoster virus (VZV), or human herpes virus type 3, is a member of the Herpesviridae family. VZV causes varicella (chickenpox) as primary infection which is a highly contagious epidemic disease globally. VZV reactivation from latency results in herpes zoster (shingle) which is a painful skin disease. Japan and the United States started to vaccinate all children in 1987 and 1995 respectively, which has reduced varicellarelated morbidity and mortality significantly. However, adverse events following administration of vaccine occur occasionally including secondary transmission and breakthrough infections. The research for safer VZV vaccine has been progressing with foreseeable advances.
伊兴旭1，甘霖1， 陈敬贤1,2，王明丽1. 水痘-带状疱疹病毒疫苗的评价与研究进展[J]. 微生物与感染, 2014, 9(4): 256-260.
YI Xing-Xu 1, GAN Lin1, CHEN Jing-Xian1,2, WANG Ming-Li1. Evaluation and research progress of varicella-zoster virus vaccines. JOURNAL OF MICROBES AND INFECTIONS, 2014, 9(4): 256-260.
