Research progress on motility, influencing factors and biological effects of Acinetobacter baumannii
ZHANG Lingling1, CHENG Tingting2, WANG Chonggang1
1. Department of Infectious Diseases, The Second Clinical Medical College of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China; 2. Department of Respiratory Medicine, Taiyuan Xishan Hospital, Taiyuan 030001, Shanxi Province, China
Abstract:Acinetobacter baumannii is a multi-drug resistant opportunistic pathogen. Its pathogenic mechanism is complex and diverse, which has posed a major threat to human health. Therefore, it is imperative to investigate its pathogenic mechanism. Bacterial motility not only plays a role in the migration of bacteria, but is also closely related to virulence, drug resistance, adhesion, chemotaxis and biofilm formation. The lack of flagella caused Acinetobacter baumannii to be thought non-motile for a long time, but further research had revealed that it could move across the wet surface by twitching and surface-associated motility. The factors affecting motility mainly include type IV pili, quorum sensing, efflux pumps, chemotaxis and blue light. This article discussed the motility, influencing factors and biological effects of motility of Acinetobacter baumannii, and provided a reference for its treatment and prevention.
张玲玲1,成婷婷2,王崇刚1. 鲍曼不动杆菌运动性、影响因素及其生物学作用的研究进展[J]. 微生物与感染, 2023, 18(2): 123-128.
ZHANG Lingling1, CHENG Tingting2, WANG Chonggang1. Research progress on motility, influencing factors and biological effects of Acinetobacter baumannii. JOURNAL OF MICROBES AND INFECTIONS, 2023, 18(2): 123-128.