微生物与感染
2024年11月29日 星期五   首页 |  主编心语 |  期刊介绍 |  编委阵容 |  投稿指南 |  出版道德 |  期刊订阅 |  联系我们 | English
微生物与感染  2023, Vol. 18 Issue (2): 123-128    DOI: 10.3969/j.issn.1673-6184.2023.02.009
  综述 本期目录 | 过刊浏览 | 高级检索 |
鲍曼不动杆菌运动性、影响因素及其生物学作用的研究进展
张玲玲1,成婷婷2,王崇刚1
1. 山西医科大学第二医院感染性疾病科,山西 太原 030001;  2. 太原西山医院呼吸科,山西 太原 030001
Research progress on motility, influencing factors and biological effects of Acinetobacter baumannii
ZHANG Lingling1, CHENG Tingting2, WANG Chonggang1
1. Department of Infectious Diseases, The Second Clinical Medical College of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China;  2. Department of Respiratory Medicine, Taiyuan Xishan Hospital, Taiyuan 030001, Shanxi Province, China
全文: PDF (717 KB)   HTML (265)
输出: BibTeX | EndNote (RIS)      
摘要: 鲍曼不动杆菌是一种多重耐药的机会致病菌,其致病机制复杂多样,对人类健康造成了严重威胁,故研究其致病机制势在必行。细菌运动不仅在细菌的迁移中起作用,还与其毒力、耐药性、黏附性、趋化性及生物膜形成等密切相关。鲍曼不动杆菌因缺乏鞭毛早期被认为不具备运动性,然而随着研究的深入发现其可通过蹭行运动及表面相关运动在潮湿的表面移动,影响其运动性的因素主要包括IV型菌毛、群体感应、外排泵、趋化系统及蓝光感应等。本文主要就鲍曼不动杆菌的运动性、影响因素及运动性的生物学作用展开讨论,并为鲍曼不动杆菌感染的预防及治疗提供参考。
服务
把本文推荐给朋友
加入我的书架
加入引用管理器
E-mail Alert
RSS
作者相关文章
张玲玲1
成婷婷2
王崇刚1
关键词 鲍曼不动杆菌运动性IV型菌毛自然转化能力    
AbstractAcinetobacter baumannii is a multi-drug resistant opportunistic pathogen. Its pathogenic mechanism is complex and diverse, which has posed a major threat to human health. Therefore, it is imperative to investigate its pathogenic mechanism. Bacterial motility not only plays a role in the migration of bacteria, but is also closely related to virulence, drug resistance, adhesion, chemotaxis and biofilm formation. The lack of flagella caused Acinetobacter baumannii to be thought non-motile for a long time, but further research had revealed that it could move across the wet surface by twitching and surface-associated motility. The factors affecting motility mainly include type IV pili, quorum sensing, efflux pumps, chemotaxis and blue light. This article discussed the motility, influencing factors and biological effects of motility of Acinetobacter baumannii, and provided a reference for its treatment and prevention.
Key wordsAcinetobacter baumannii    Motility    Type IV pili    Natural transformation ability
ZTFEL:  R378  
基金资助:山西省应用基础研究计划(20210302123279)
通讯作者: 王崇刚   
引用本文:   
张玲玲1,成婷婷2,王崇刚1. 鲍曼不动杆菌运动性、影响因素及其生物学作用的研究进展[J]. 微生物与感染, 2023, 18(2): 123-128.
ZHANG Lingling1, CHENG Tingting2, WANG Chonggang1. Research progress on motility, influencing factors and biological effects of Acinetobacter baumannii. JOURNAL OF MICROBES AND INFECTIONS, 2023, 18(2): 123-128.
链接本文:  
http://jmi.fudan.edu.cn/CN/10.3969/j.issn.1673-6184.2023.02.009     或     http://jmi.fudan.edu.cn/CN/Y2023/V18/I2/123

版权所有 © 2008 《微生物与感染》编辑部
地址:上海市医学院路138号 邮编:200032
Tel:021-54237633 Fax:021-64434224    E-mail:jmi@fudan.edu.cn
本系统由北京玛格泰克科技发展有限公司设计开发  技术支持:support@magtech.com.cn