Abstract:Uropathogenic Escherichia coli (UPEC) is the major cause of urinary tract infections worldwide. Outer membrane protease T (OmpT) , as a putative uropathogenic virulence factor , is found more frequently in UPEC than in fecal isolates. This review covers the current progress on substrate specificity of OmpT, resistance to cationic antimicrobial peptides, roles in the fibrinolytic system and bacterial adhesion and invasion.
惠长野1,黄胜和2,曹虹2,张艳芳1. 大肠埃希菌外膜蛋白酶T毒力机制的研究进展[J]. 微生物与感染
, 2012, 7(4): 233-238.
HUI Chang-Ye1, HUANG Sheng-He2, Cao Hong2, Zhang Yan-Fang1. Progresses on the virulence mechanism of outer membrane protease T from Escherichia coli. Journal of Microbes and Infections, 2012, 7(4): 233-238.