Risk factors of infections caused by linezolid-resistant Enterococcus faecalis
MA Xiaoyu, PU Zhangya,YAO Weiming, CHEN Zhong, WANG Hongyan, CHENG Hang, DENG Xiangbin, LI Duoyun, ZHENG Jinxin, DENG Minggui, LIU Xiaojun, DENG Qiwen, YU Zhijian
Department of Infectious Diseases, Shenzhen Nanshan District People’s Hospital, Shenzhen Key Laboratory for Endogenous Infection, Shenzhen 518052, China
Abstract:To analyze the risk factors of infections caused by linezolid-resistant Enterococcus faecalis (E. faecalis), 165 cases from Shenzhen Nanshan District People’s Hospital with E. faecalis infection recorded from January 2010 to September 2015 were studied. The patients were divided into linezolid-sensitive group and linezolid-resistant/intermediate group. E. faecalis mainly came from urine culture (53.94%), and then wound secretion culture (21.82%) and bloodstream culture (6.06%). E. faecalis infection was mainly found in Department of Urology (35.76%) and Department of Hepatobiliary Surgery (9.70%). Both univariate analysis and logistic regression analysis showed that carbapenem exposure and indwelling catheter were associated with linezolid-resistant E. faecalis infections. The results suggest that the clinical application of carbapenems should be strictly controlled, and the management of nosocomial infection should be strengthened.
马孝煜,蒲彰雅,姚伟明,陈重,王红燕,程航,邓向斌,李多云,郑金鑫,邓名贵,刘晓军,邓启文,余治健. 耐利奈唑胺粪肠球菌感染的危险因素分析[J]. 微生物与感染, 2017, 12(4): 217-221.
MA Xiaoyu, PU Zhangya,YAO Weiming, CHEN Zhong, WANG Hongyan, CHENG Hang, DENG Xiangbin, LI Duoyun, ZHENG Jinxin, DENG Minggui, LIU Xiaojun, DENG Qiwen, YU Zhijian. Risk factors of infections caused by linezolid-resistant Enterococcus faecalis. JOURNAL OF MICROBES AND INFECTIONS, 2017, 12(4): 217-221.