Abstract：Objective To report a rare case of bacteremia caused by Lactobacillus salivarius in gastric cancer patient with liver metastasis, and to discuss the risk of opportunistic infection caused by Lactobacillus salivarius. Methods The diagnosis and treatment of bloodstream infection in this patient were retrospectively analyzed. VITEK 2 compact automatic bacterial analyzer and Antu autof ms1000 automatic microbial mass spectrometry detection system were compared, and 16S rRNA sequencing was also used to identify the strains. TDR ANA-AST was used for drug sensitivity test to provide clinical medication guidance. Results Three bottles of blood culture were positive in 2-3 days after operation. Gram positive bacilli were detected by direct smear and colonoscopy. The strains was identified as Lactobacillus acidophilus by VITEK 2 compact. Antu biological Autof ms1000 automatic microbial mass spectrometry detection system and 16S rRNA sequencing were all identified the strains as Lactobacillus salivarius. After using imipenem for anti infection treatment, the blood culture was negative. Conclusion Lactobacillus salivarius was isolated from the blood culture of a gastric cancer patient with liver metastasis in Shanghai East Hospital. The drug sensitivity test provides guidance for clinical drug use.
倪丽君 郭建. 唾液乳杆菌引起的胃恶性肿瘤肝转移患者菌血症[J]. 微生物与感染, 2022, 17(5): 312-316.
LiJun NI guo jian. Bacteremia caused by Lactobacillus salivarius in a gastric cancer patient with liver metastasis. JOURNAL OF MICROBES AND INFECTIONS, 2022, 17(5): 312-316.
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