CHEN Shenglin1*, XIAO Man2*, LI Zhaozhong3, XU Zhikai1, HAN Qi1, FENG Dongfang1, DENG Yan1, YIN Zuoming1
1. General Hospital of Tibet Military Area Command of PLA, Lhasa 850007, Tibet Autonomous Region, China; 2. Chengdu Western Hospital, Chengdu 610036, Sichuan Province, China; 3. General Hospital of Western Theater Command of PLA, Chengdu 610083, Sichuan Province, China
Abstract：Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is the causative agent of the coronavirus disease 2019(COVID-19), which spreads rapidly in humans and endangers global health and economy. There are no specific and effective antiviral drugs for the treatment of COVID-19 currently. To infect host cells successfully for a virus, receptor binding and virus internalization are considered to be the initial steps. A key to combat SARS-CoV-2 infection is to investigate the viral receptors, which determine its infectivity and host range. The discovery and identification of cell receptors for SARS-CoV-2 will provide new therapeutic targets for COVID-19. This article reviews the recent findings on the entry and attachment receptors for SARS-CoV-2.
2023, Vol. 18 
