口腔微生态和肠道微生态是微生态系统的重要组成部分，两者之间关系密切，近年来两者之间的交互作用成为研究热点。本文结合近期研究进展，系统介绍两者在健康状态下的交互作用及在疾病状态下的交互变化，为诊断及治疗提供新的启示。

Oral and gut microbiota are important components of microbiota system, there is a close relationship between them. In recent years, the interaction between them has become a research hotspot. Combined with the recent research progress, this paper systematically introduces the interaction between them in the state of health and the interaction changes in the state of disease, so as to provide new enlightenment for diagnosis and treatment.