摘要：本研究旨在分析罕见沙门菌——浦那沙门氏菌（Salmonella Poona）的生物学特性及分子特征，为沙门菌临床治疗和防治提供科学依据。采用细菌学鉴定、血清分型、药敏试验和全基因组测序技术，来分析其生物学特性及分子特征。结果显示生化鉴定为沙门菌属；血清分型为O22:Hz:H1、6；对大部分抗生素耐药，携带的耐药基因与毒力基因类型众多。本研究证实长春市首次分离的浦那沙门菌菌株耐药性及毒力较强，应引起关注。
Abstract
Abstract: This study aims to analyze the biological characteristics and molecular features of Salmonella Poona, a rare serotype of Salmonella, to provide scientific evidence for clinical treatment and prevention. Bacteriological identification, serotyping, drug sensitivity testing, and whole genome sequencing were employed to investigate its biological and molecular profiles. Results demonstrated that the strain was biochemically confirmed as Salmonella genus with serotype O22:Hz:H1、6. The isolate exhibited resistance to most antibiotics and harbored a diverse array of resistance and virulence genes. This research confirms the first isolation of a multidrug-resistant and highly virulent Salmonella Poona strain in Changchun City, highlighting the need for heightened attention to this pathogen.
关键词
关键词：浦那沙门菌 /
药敏试验 /
全基因组测序
Key words
Key Words: Salmonella Poona /
drug sensitivity testing /
whole genome sequencing
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