浦那沙门菌(Salmonella Poona)是沙门菌的一种罕见血清型。本研究以长春市儿童医院从食源性疾病主动监测项目中报告的一例患者粪便样本中分离到的沙门菌株为研究对象，采用细菌学鉴定、血清分型、药敏试验和全基因组测序技术分析其生物学特性及分子特征。结果显示，此菌株通过生化鉴定为沙门菌属，血清学分型鉴定结果为浦那沙门菌；对大部分抗生素耐药，且携带的耐药基因与毒力基因类型众多。本文证实，长春市首次分离的浦那沙门菌菌株的耐药性及毒力较强，应引起关注。本研究分析了浦那沙门菌的生物学特性及分子特征，旨在为沙门菌临床治疗和防治提供科学依据。

Salmonella Poona is a rare serotype of Salmonella. This study was conducted on a Salmonella strain isolated from the fecal sample of a patient reported by the active surveillance project of foodborne diseases in Changchun Children’ Hospital. Bacteriological identification, serotyping, drug sensitivity testing, and whole genome sequencing were employed to investigate its biological and molecular profiles. Results demonstrated that this strain was biochemically confirmed as Salmonella and identified as Salmonella Poona by the serological typing. The isolate exhibited resistance to most antibiotics and harbored a diverse array of resistance and virulence genes. This research confirms the first isolation of a multidrug-resistant and highly virulent Salmonella Poona strain in Changchun City, highlighting the need for heightened attention to this pathogen. This study aimed to analyze the biological characteristics and molecular features of Salmonella Poona to provide scientific evidence for clinical treatment and prevention.