新型冠状病毒肺炎(简称新冠)疫情仍在发展，新型冠状病毒变异株的出现致使其传染性和致病性增强，部分国家的政府和民众防控措施松懈导致某些地区疫情加剧。新型冠状病毒疫苗广泛使用后，接种情况会影响疫情发展。本文主要阐述新冠疫情与疫苗接种、病毒变异的关联性，接种疫苗存在的问题及其应对措施，并建议在加快疫苗接种的同时应做好各项新冠防控工作。

The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still develops. Because several viral variants have increased transmissibility and/or virulence, while some governments and people have slackened their pandemic control measures, the COVID-19 situations in some countries and regions have become worsen. After worldwide rollout of SARS-CoV-2 vaccines, different vaccination rates have different effect on local pandemic situations. This paper covers the relationship between COVID-19 situations and the rollout of SARS-CoV-2 vaccines as well as viral variants, the difficulties on COVID-19 vaccination and their solutions, and recommends to speed up vaccination, at the same time, various preventive and control measures on COVID-19 should be carry out seriously.