Abstract：To analyze the clinical characteristics, pathogens and drug sensitivity of children urinary tract infection (UTI), so as to help pediatricians better manage UTI in children, clinical data of 591 hospitalized children with UTI from January, 2014 to February, 2021 were collected and analyzed. The results showed that the incidence of male and female, clinical manifestations and co-exist diseases were statistically significant in different age groups (P<0.05). The common pathogens were mainly E. coli and Enterococcus faecium. The proportion of pathogens in 2014-2017 and 2018-2021 was statistically significant (P<0.05). The enzyme-producing rate of E. coli decreased during 2018 and 2021, and the enzyme-producing strains showed higher drug resistance rate than the non-enzyme-producing strains, and the resistance rate of some antimicrobials decreased in recent years. The drug resistance rate of Enterococcus faecium to gentamycin and levofloxacin was higher than 50%, and the sensitivity rate to daptomycin and macrodantin was higher than 60%. It was concluded that the incidence, clinical manifestations and co-exist diseases in children with UTI varied with ages. In recent years, the proportion of gram-negative bacteria show an upward trend, while the proportion of gram-positive bacteria show a downward trend, and β lactamase-producing E．coli and Enterococcus faecium are resistant to many commonly used antibiotics.
2023, Vol. 18 
