肠道菌群与相关疾病

曹蕾,吴健

微生物与感染 ›› 2017, Vol. 12 ›› Issue (5) : 264-269.

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微生物与感染 ›› 2017, Vol. 12 ›› Issue (5) : 264-269.
特约专稿

肠道菌群与相关疾病

  • 曹蕾,吴健
作者信息 +

Intestinal microbiota and related diseases

  • CAO Lei, WU Jian
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文章历史 +

摘要

近年来肠道菌群的研究发展迅速,肠道菌群对宿主消化、代谢和免疫功能的影响逐渐被人们所熟知并重视。大量研究提示,肠道菌群的改变可能引发代谢、肝脏和肠道等方面的多种相关疾病。因此,研究肠道菌群对宿主健康及疾病的影响尤为重要,也能为预防和治疗肠道菌群相关疾病提供建议。

Abstract

The potential impact of intestinal microbiota on human health and related diseases is an emerging research field. Growing evidence of the role of intestinal microbiota in host digestion, metabolism and immune function has drawn great attention from the scientific community. Changes of gut microbiota may lead to a variety of disorders in metabolic system, liver and intestinal tract. Therefore, further studies on how microbiota exactly affects host health and related diseases are of fundamental importance in providing valuable guidance in the prevention and treatment of many diseases which have no available effective therapeutics.

关键词

肠道菌群 / 宿主健康 / 代谢性疾病 / 酒精性肝病 / 非酒精性脂肪性肝病 / 肝硬化 / 炎症性肠病

Key words

Gut microbiota / Host health / Metabolic disease / Alcoholic liver disease / Nonalcoholic fatty liver disease / Hepatic cirrhosis / Inflammatory bowel disease

引用本文

导出引用
曹蕾,吴健. 肠道菌群与相关疾病[J]. 微生物与感染. 2017, 12(5): 264-269
CAO Lei, WU Jian. Intestinal microbiota and related diseases[J]. Journal of Microbes and Infections. 2017, 12(5): 264-269

基金

国家自然科学基金 (81272436、81572356),科技部政府间创新合作重点专项(2016YFE0107400),上海市科学技术委员会科研计划项目(16140903700)


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